Pharmacology

 

Xenometrics offers services that allow Biotechnology and Pharmaceutical companies make informed real time decisions in the selection and development of new drug candidates.

Safety Pharmacology

  • Cardiovascular
    • In-vivo Radiotelemetry
      • NHP
      • Canine
    • In-vitro
      • hERG
      • Multicellular preparations
  • Central Nervous System
    • Irwin
    • Figure-eight maze
    • Cognition (Water maze and passive avoidance)
    • FOB
      • Rodent
      • NHP
  • Respiratory
    • Plethysmography
    • Blood gas analysis

 

E-mail: Pharma@xeno-metrics.com 

ADME

 

 

Concise investigation of drug metabolism is essential to the drug discovery process. The drug discovery services offered by Xenometrics are strategically selected to support pharmaceutical companies of varying sizes. All standard routes of administration are offered

Pharmacokinetics / TK

  • Radiolabelled/Non-radiolabelled
  • Mass Balance/Excretion
    • NHP
    • Canine
    • Rodents

 

 

E-mail: Adme@xeno-metrics.com 

Drug Discovery

Our capabilities for drug discovery are varied and customized to suit your needs.

  • Candidate screening
  • Multiple species and screening approaches
  • Cost effective Non-GLP protocols available
  • Bile duct cannula models to support met ID

E-mail: Drugdis@xeno-metric.com 

Affiliates & Strategic Alliances

Toxicology

  • Acute/Subacute/Chronic
    • Rodents & Non-rodents
  • Carcinogenicity
  • DART
    • One or Two generation
    • Developmental Neurotoxicity
    • Fertility and Embryonic development

Pathology

  • Necropsy
  • Histology
  • Histopathology
  • Clinical Chemistry
  • Hematology

E-mail: Tox@xeno-metrics.com 

Cardiovascular

  • Drug-eluting Stents
  • Thoracic Surgery
  • Coronary and Peripheral Stents/Vascular Devices
  • Cardiac Device Implantation
  • PFO Screening and Device Evaluation

Orthopedics

  • Joint/Cartilage Models
  • Spine Models
  • Bone Repair Models
  • Models of Osteopenia and Trabecular Plate Perforation

Surgical Models

  • Surgical Product Modeling
  • Cannulation, VAP, Medical device

Drug Discovery/Development

Toxicology

  • Mini Swine/Canine

Pharmacokinetics

  • Mini Swine/Canine/Goat/Sheep/Poultry
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